The Tech Tribune staff has compiled the very best tech startups in St. Petersburg, Florida. In doing our research, we considered several factors including but not limited to:

1. Revenue potential
2. Leadership team
3. Brand/product traction
4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. CrossBorder Solutions

Founded: 2016

Also honored in: 2022 Best Tech Startups in St. Petersburg

“CrossBorder Solutions is the global leader in technology-driven tax solutions. Our advanced AI tax expert can help your business move from the old ways to the new with greater clarity, efficiency and more cost-effectively than ever before.”

2. Dexalot

Founded: 2021

“Dexalot operates a trading platform that brings a viable decentralized exchange. Its platform creates an inclusive trading environment that can rival centralized exchanges, enabling people to trade at low fee rates to maximize their returns. The company was founded in 2021 and is based in St. Petersburg, Florida.”

3. SKUxchange

Founded: 2018

Also honored in: 2022 Best Tech Startups in St. Petersburg

“An innovative payments solution, SKUx gives brands and retailers the power to deliver secure, intuitive digital offers anywhere, anytime, at the speed of today’s consumer. The company’s patented platform-as-a-service combines first-party data, offer details, serialization, funding, and settlement to increase customer trust, loyalty and create new opportunities for consumer engagement. The result – new incremental revenue, improved efficiency, and laser sharp transparency for all industry stakeholders.”

4. Viirtue

Founded: 2018

“Viirtue is an award-winning wholesale voice & UCaas provider. Viirtue’s ViiBE platform transforms MSPs, VARs, ITSPs, and Telcos into digitized business communications providers. Check out our new lightning fast white label payment portal where your customers can manage and pay their subscriptions, e-sign quotes and other documents, and so much more.”

5. RxLive

Founded: 2017

Also honored in:

• 2022 Best Tech Startups in St. Petersburg
• 2021 Best Tech Startups in St. Petersburg
• 2020 Best Tech Startups in St. Petersburg

“RxLive integrates clinical pharmacists into the healthcare team to create significant financial and clinical value. Implementing and maximizing this value is a discipline we call Value‑Based Pharmacy™. We are a concierge telehealth pharmacy service that connects patients with expert pharmacists in a secure, private and personal way.”

6. 5×5 Technologies

Founded: 2016

“5×5 combines AI, ML and intelligent digital twins to help owners of communications infrastructure maximize ROI, safety and operations.”

7. Metaverse Game Studios

Founded: 2020

“Metaverse Game Studios is a cross-platform game development and publishing company.

Currently, we are working on Angelic, a narrative multiplayer Strategy RPG set in a collaborative sci-fi universe.”

8. Enlyt Health

Founded: 2019

“Welcome to the Patient Engagement Cloud – A turnkey platform to cultivate 1:1 relationships with patients and providers to deliver innovation across health systems.”

9. Lonestar

Founded: 2021

“Recently emerging from stealth: venture to extend terrestrial data services to the Moon for both the terrestrial archival market and to support space operations with data analytics, archival services and broadband relay to terrestrial public and private clouds. Founded by a proven team of experts from Cloud and Space verticals, Lonestar Data Holdings Inc. is pioneering the future of cislunar services.”

10. Code-X

Founded: 2018

Also honored in: 2022 Best Tech Startups in St. Petersburg

“Code-X is the data security company that simplifies how organizations protect the world’s most sensitive information and systems. Powered by proprietary lattice-based technology, Code-X delivers the industry’s first system and device-friendly platform that applies impermeable security from the moment of data creation throughout its entire life cycle.”