2021 Best Tech Startups in Ohio

Powered by CrunchbaseThe Tech Tribune staff has compiled the very best tech startups in Ohio. In doing our research, we considered several factors including but not limited to:

  1. Revenue potential
  2. Leadership team
  3. Brand/product traction
  4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. Olive


Founded: 2012

Also honored in:

“Olive is on a mission to build meaningful artificial intelligence that empowers and scales humans to achieve more than ever before. We are pioneers working to make the AI revolution both powerful and beneficial to humankind. We are putting a blue collar on AI and letting it do what machines can do best– and leaving the tasks that require creativity, empathy, and passion to people.”

2. RVshare


Founded: 2013

Also honored in:

“RVshare offers the largest selection of trusted RV rentals in the country. Founded in 2013 in Akron, Ohio, we connect RV owners and renters, offering an additional source of income for RV owners and the option for a memorable vacation for renters. Renters can search through thousands of short- and long-term RV rental options, including Luxury Class A Diesel Pushers, Class B Camper Vans, Class C Motorhomes, and Travel Trailers, and filter to search and compare RV rental prices, features, reviews, and more. The secure RVshare payment system provides a $10,000 Peace of Mind Guarantee, a 24-hour travel concierge, nationwide insurance, and free roadside assistance. RVing is a convenient, exciting way to travel, and eliminates the challenges and costs of finding hotel accommodations.”

3. Enable Injections

Enable Injections

Founded: 2011

Also honored in: 2021 Best Tech Startups in Cincinnati

“Cincinnati-based Enable Injections is a healthcare technology innovator and startup developing and manufacturing large-volume wearable drug delivery systems – aiming to transform patient access to care by supporting flexible delivery, superior patient experience, and improved healthcare system value and economics.

Once approved by regulatory authorities, Enable’s wearable enFuse® drug delivery platform enables AnywhereCare TM – large-volume therapeutic delivery via subcutaneous administration in a healthcare clinic, with a healthcare professional at a patient’s home, or via self-administration at home.

Enable’s enFuse® utilizes standard container closure systems to deliver large volumes up to 50 mL of high-viscosity pharmaceutical and biopharmaceutical therapeutics. For more information, visit us at”

4. Beam Dental

Beam Dental

Founded: 2012

Also honored in:

“Beam Dental is a dental benefits company that offers employers a fundamentally unique approach to dental coverage by incorporating dental hygiene behavior into policy pricing while delivering world class support and service. All of Beam’s plans also include Beam Perks, a quarterly subscription service with an electric toothbrush, replacement heads, toothpaste, and floss. Beam makes it easy to find and access dental services with the tap of a finger from a broad, nationwide network of dentists.”

5. OAREX Capital Markets, Inc.

OAREX Capital Markets, Inc.

Founded: 2013

Also honored in: 2021 Best Tech Startups in Cleveland

“OAREX is a digital revenue exchange where online businesses can exchange future digital payouts and sales for upfront capital. Backed by East West Bank and Arena Investors with a $100M credit facility.”



Founded: 2017

Also honored in: 2020 Best Tech Startups in Ohio

“VNDLY is a next-generation technology platform and marketplace designed for hiring managers at large corporations and vendor account management teams to come together on a common platform for end-to-end contractor recruiting, on-boarding, and full lifecycle management.”

7. READY Robotics

READY Robotics

Founded: 2016

Also honored in:

“READY Robotics empowers manufacturers to be more competitive through our line of easy-to-use industrial robotic systems. Our robotic solutions require minimum installation downtime, no robotic experience necessary and no Capital Expenditure needed. We deploy Robots as a Service.”

8. 80 Acres Farms

80 Acres Farms

Founded: 2015

“80 Acres Farms is an indoor farming company providing customers pesticide free, just-picked leafy greens, herbs, microgreens, and vine crops, including the world’s only tomatoes and cucumbers grown completely indoors using the most-efficient, LED lighting. The company delivers high quality and nutritious products by locating its indoor farms close to customers. 80 Acres is able to eliminate the costs, time and environmental impact of cross-country transportation, providing customers with a fresher, longer-lasting product while drastically reducing food waste. 80 Acres distributes to major national grocers, local retailers, restaurants, and food service companies from its six farm facilities in Ohio, Arkansas, North Carolina, and Alabama.”

9. Matic Insurance

Matic Insurance

Founded: 2014

“Since 2014, Matic has changed the landscape of the insurtech industry by integrating insurance within the home and auto ownership experience. Today, Matic’s digital insurance marketplace has over 30 A-rated home and auto carriers, as well as distribution partners in industries ranging from mortgage origination and servicing to banking, auto financing, and much more.”

10. Physna


Founded: 2015

Also honored in: 

“Physna, short for “Physical DNA”, is a revolutionary technology that compares and analyzes 3D models through shape search, quality control and more in various industries. Physna is most commonly used in engineering and CAD design, manufacturing, aerospace, defense and diverse types of inspection automation. Physna is a fast-growing software company based in downtown Cincinnati, Ohio and is a Siemens partner as well as a technology provider to NASA Space Camp, Purdue University, etc.”