2021 Best Tech Startups in Philadelphia

Powered by CrunchbaseThe Tech Tribune staff has compiled the very best tech startups in Philadelphia, Pennsylvania. In doing our research, we considered several factors including but not limited to:

  1. Revenue potential
  2. Leadership team
  3. Brand/product traction
  4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. goPuff


Founded: 2013

Also honored in: 

“goPuff delivers everyday essentials, from cleaning supplies, home needs and OTC medications to food and drinks in just minutes. With our own centrally located facilities in every local market we serve, goPuff delivers thousands of products quickly for a flat $1.95 delivery charge. goPuff is open 24/7 in most areas and late night everywhere else to bring you what you need, when you need it most.

Headquartered in Philadelphia, goPuff was founded in 2013 and currently operates over 200 facilities in 500+ cities across the U.S., including Atlanta, Boston, Chicago, Dallas, Denver, Philadelphia, Phoenix, Seattle, Pittsburgh, Washington, D.C., and many more.”

2. Guru


Founded: 2013

Also honored in:

“Guru is a collaborative knowledge management solution where answers find you–everywhere, every time.

By empowering these teams in-context with the knowledge they need to respond to customer questions, they can stop spending time hunting down information and instead focus on what matters most — their customers.”

3. HealthVerity, Inc.


Founded: 2014

Also honored in:

“HealthVerity is a leading provider of technologies and software tools that enable healthcare providers, such as Pharmaceutical manufacturers, Hospitals and Payers, to discover, license and integrate patient data from a wide range of traditional and emerging data sources to build the optimal patient data set.”

4. Crossbeam


Founded: 2018

“Crossbeam is a collaborative intelligence platform that helps companies build more valuable partnerships. It serves as an escrow service for data, allowing companies to find overlapping customers and prospects, while keeping the rest of their data private and secure. Not only can Crossbeam help you prioritize the right partners to work with, it can also help you measure the impact those partnership programs have on your business.”

5. Exyn Technologies

Exyn Technologies

Founded: 2014

Also honored in: 

“Exyn Technologies was established in 2014 to commercialize decades of ground-breaking research in aerial robotics, drone swarms, multi-modal sensor fusion, 3D mapping, obstacle avoidance, and autonomous navigation & planning.

Exyn’s focus is on developing software for aerial robots so they can operate in GPS-denied environments, without human control, prior information, or pre-existing infrastructure (e.g. no motion capture system).”

6. Houwzer


Founded: 2015

Also honored in: 2020 Best Tech Startups in Philadelphia

“Houwzer is a modern, socially responsible real estate agency for savvy homeowners. We’ve rebuilt the real estate brokerage model around the customer with technology and a team of full service, salaried Realtors. Home sellers save an average of $15,000 with our listing agents, while home buyers trust our team’s focus on buyer goals, not commissions. We take pride in giving back to our communities and maintaining an average review of 4.9 out of 5 stars from over 500 client reviews.”

7. Fishtown Analytics

Fishtown Analytics

Founded: 2016

“Since 2016, Fishtown Analytics has been on a mission to help analysts create and disseminate organization knowledge. Fishtown Analytics pioneered the practice of analytics engineering, built the primary tool in the analytics engineering toolbox–dbt, and has been fortunate enough to see a fantastic community coalesce to help push the boundaries of the analytics engineering workflow. Today, there are 1,700 companies using dbt Core, 250 customers of dbt Cloud, and 5,000 global members of the dbt Slack community.”

8. Proscia Inc.

Proscia Inc.

Founded: 2014

Also honored in: 2020 Best Tech Startups in Philadelphia

“Proscia is fighting cancer with intelligent software that changes the way the world practices pathology. Join us.”

9. Picwell


Founded: 2012

Also honored in: 2020 Best Tech Startups in Philadelphia

“Picwell is a Philadelphia-based, healthcare technology company providing leading enterprise solutions to enhance healthcare benefits and improve the consumer experience. Picwell’s flagship offering is a SaaS-based decision support product that uses artificial intelligence to match individuals to the right health benefits during enrollment by predicting future care considerations, estimating out-of-pocket expenses, and accounting for individual preferences. Other solutions support consumerism and high-deductible health plan adoption, consumer engagement, and risk management.

We are on a mission to transform choice in healthcare. More than 200 million people choose benefits each year, but the complexity of the healthcare system makes it challenging to get the right protection based on individual care and cost needs. We imagine a future where healthcare benefits are simple – and people can make the right choice with confidence.”

10. RoundTrip


Founded: 2017

Also honored in: 2020 Best Tech Startups in Philadelphia

“Roundtrip is the leading digital transportation marketplace for better health outcomes. We provide a simple, comprehensive patient ride ordering software that makes available a community of ride providers who complete the transport. The company is leading the industry in reducing patient no-shows through improved ride management.

Roundtrip is built for healthcare professionals — care coordinators, social workers, nurses and other transport requestors —and offers easy-to-use online and mobile platforms that connect patients with non-emergency medical transportation (NEMT). Roundtrip is a comprehensive
solution which supports all levels of transport: medical cars, wheelchair vans, stretcher vehicles, ALS/BLS, all payors, and all trips delivered when and where they are needed.”