2022 Best Tech Startups in Winston-Salem

Powered by CrunchbaseThe Tech Tribune staff has compiled the very best tech startups in Winston-Salem, North Carolina. In doing our research, we considered several factors including but not limited to:

  1. Revenue potential
  2. Leadership team
  3. Brand/product traction
  4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. Fluree


Founded: 2017

Also honored in: 2021 Best Tech Startups in Winston-Salem

“Fluree is a cryptographically-secure semantic graph database with a cloud-native architecture. Build your data ecosytem:”

2. F5 Sports

F5 Sports

Founded: 2017

Also honored in: 2021 Best Tech Startups in Winston-Salem

“F5 Sports transforms data from body movement into real-time, actionable insights that improve learning and maximize human performance. We put the capabilities of a pitching lab inside a regulation size baseball to provide insights into athletic performance. Our pitchLogic ball and mobile app help players of all levels train more effectively and win more games.”

3. OrbitalRx


Founded: 2017

Also honored in: 2021 Best Tech Startups in Winston-Salem

“We see a new future for healthcare. One that sets a higher bar for what we expect and accept from the systems that provide care services for our loved ones and communities.

At OrbitalRX, we are building the next generation of solutions to make health-systems safer, more efficient, and cost effective. If you’d like to use your skills for creating the tools that healthcare needs in order to build a new, more sustainable future then we’d like to talk to you.”

4. Wellnecity


Founded: 2015

Also honored in: 2021 Best Tech Startups in Winston-Salem

“Wellnecity leverages technology and unparalleled service to empower self-insured employers to save up $2,000 per employee on health benefits. Our ProActive Benefits Management™ Platform uses superior business intelligence and ongoing support to help employers take control of their spend, eliminate waste, and make better choices, without disrupting their current plan structure or vendor relationships.

With U.S. healthcare costs continuously rising and employee cost-sharing reaching its limits, employers have a real headache on their hands. Insurance carriers do not provide the necessary insight and support because they do not gain from reducing employer plan costs; the status quo is working quite well for them.”

5. Titan Industries

Titan Industries

Founded: 2018

“Titan is a new, intelligent mining management software suite and hashpower marketplace that will increase the ease, efficiency, and profitability of cryptocurrency mining – all while increasing the useful lifespan of mining equipment. Titan is built by miners for miners to make mining easy, profitable, and scalable.”

6. Vispa


Founded: 2018

“Vispa is a collaborative team of passionate veteran process management experts, technologists, and business leaders on a mission to bring efficiency, effectiveness and, above all, simplicity to an overly complex process of revenue cycle management for healthcare organizations.

For revenue cycle leaders of hospitals who want to increase efficiency, improve employee effectiveness, eliminate excessive costs, and quickly increase cash flow, Vispa is an intuitive, web-based software solution with integrated analytics. Vispa takes the guesswork out of achieving your financial goals with a priority-driven operational workflow, a clean, user-first interface, and unmatched implementation time.”



Founded: 2017

Also honored in: 2021 Best Tech Startups in Winston-Salem

“The kick-start to launch SWIPEBY is rooted in a day-to-day observation: If you want to enjoy a nice meal at home without doing the cooking yourself, the options you have are just not satisfying. Either you need to wait a long time for your delivery, especially in suburban markets, or you end up queuing at one of the big drive-thrus, which does not offer the meal you really want.

With SWIPEBY we launched a food-ordering app which turns any restaurant into a “drive-thru”. SWIPEBY combines the whole world of great food with a great user experience.”

8. XPAND Gaming

XPAND Gaming

Founded: 2014

“Social media and networking platform for gamers. Place where you can find friends, grow your online presence and make money!”