2021 Best Tech Startups in Plano

Powered by CrunchbaseThe Tech Tribune staff has compiled the very best tech startups in Plano, Texas. In doing our research, we considered several factors including but not limited to:

  1. Revenue potential
  2. Leadership team
  3. Brand/product traction
  4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. Aligned


Founded: 2015

“Aligned is an infrastructure technology company that offers adaptable colocation and build-to-scale solutions to cloud, enterprise, and managed service providers. Our intelligent infrastructure allows densification and vertical growth within the same footprint, enabling customers to scale up without disruption, all while maintaining industry-leading Power Usage Effectiveness (PUE). By reducing the energy, water and space needed to operate, our data center solutions, combined with our patented cooling technology, offer businesses a competitive advantage by improving reliability and their bottom line.”

2. AlixaRx


Founded: 2012

Also honored in: 2020 Best Tech Startups in Plano

“AlixaRx provides advanced pharmacy services to post‐acute healthcare facilities through a new model that leverages technology to deliver medication therapy management. AlixaRx is a differentiated approach because it utilizes a combination of clinical pharmacists, automated dispensing units, and electronic medication cabinets to meet the medical needs of patients and residents at each facility. AlixaRx delivers improved safety, creates better access to medications, and produces time and cost savings in post‐acute, skilled nursing, and numerous other healthcare settings.”

3. BaiCells Technologies

BaiCells Technologies

Founded: 2014

“Baicells is a customer oriented high-tech company providing innovative and affordable LTE solutions, which can be used by mobile operators, fixed/wireless operators and ISPs, MNO/MVNO, governments and enterprise private networks.

With advanced innovative technology from America and precise manufacturing capability from China, Baicells focuses on wireless broadband access, operation platforms, and next generation wireless solutions. Baicells’​ products include indoor and outdoor Small Cells, Gateway,Cloud based EPC, Cloud based O&M, CPE, Antenna, etc.”

4. Critical Start

Critical Start

Founded: 2012

Also honored in: 2020 Best Tech Startups in Plano

“CRITICALSTART is leading the way in Managed Detection and Response (MDR) services. As the MDR experts that leave nothing to chance, the company developed the industry’s only cloud-based Security Orchestration, Automation and Response (SOAR) platform that resolves 99% of security events to eliminate compromise and stop breaches. Visit for more information.”

5. OneDine


Founded: 2017

Also honored in: 2020 Best Tech Startups in Plano

“OneDine is the single, simple, cost-effective tableside-ordering and payment solution that leverages the power of data to take your restaurant brand to the next level.

By capturing each guest’s dining experience, OneDine gives you competitive insights into your guests’​ dining journey, allowing you to pinpoint exactly where your greatest growth opportunities lie.

With dozens of customizable features and functions, OneDine is your 360-degree, data-driven solution for elevating your guest experience, optimizing your marketing, and unleashing your sales like never before.”

6. OpenKey


Founded: 2015

Also honored in: 

“Unlock Guest Experiences with the Universal Standard for Mobile Keyless Entry.

OpenKey is an app that allows hotel guests to open their hotel room with their smartphone.
Guests enjoy keyless room entry & “skip the front desk” features while Hotel Owners benefit from having one standardized door opening solution.

OpenKey works with brand apps or as a standalone solution, so hotels of any size can do big things.”

7. DoctorLogic


Founded: 2013

“DoctorLogic is an all-in-one website marketing platform created exclusively for healthcare providers. The DoctorLogic software was invented to power custom-designed websites for patient acquisition, retention marketing, and practice insights that help providers connect with more people.”

8. Cien


Founded: 2016

Also honored in: 2020 Best Tech Startups in Plano

“Using over 100 AI models, Cien uncovers the skills and attributes that impact sales performance such as product knowledge, work ethic, activity management and closing ability.

Contact us if you are interested in joining an A+ team, or request a free assessment to get your sales team to 100% quota.”

9. Axenic Health Solutions

Axenic Health Solutions

Founded: 2017

“Axenic Health Solutions was founded with one clear mission: identify the most innovative and paradigm altering infection prevention solutions available in the world and deliver them to U.S. healthcare providers – seamlessly and cost effectively.

We bring a fully integrated suite of products, methodologies and services, all clinically tested at leading clinical organizations, proven to drive transformative results.”

10. Aavenir


Founded: 2019

“Aavenir’s next-gen Source-to-Pay suite revolutionizes age-old procurement processes by using the latest Machine Learning and Natural Language Processing technologies to reduce cycle time, yet offering insightful best practices suggestions based on historical data. For example, Aavenir’s Contractflow – Contract Lifecycle Management (CLM) product solves the hardest text analytics problems for risk and obligation management while, Invoiceflow – Accounts Payable (AP) automation product solves multi-vendor invoice data extraction and processing problems by harnessing the power of AI & ML technologies.

Aavenir SaaS-based source-to-pay solutions are powered by the most advanced cloud-based ServiceNow platform that is delivering unified digital workflows to create great experiences and unlock productivity for approximately 5,400 enterprise customers worldwide, including Fortune 500 companies.”