2023 Best Tech Startups in Baltimore

Powered by CrunchbaseThe Tech Tribune staff has compiled the very best tech startups in Baltimore, Maryland. In doing our research, we considered several factors including but not limited to:

  1. Revenue potential
  2. Leadership team
  3. Brand/product traction
  4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. Delfi Diagnostics

Delfi Diagnostics

Founded: 2019

Also honored in: 

“DELFI uses artificial intelligence and whole genome sequencing to sensitively detect unique patterns of DNA fragmentation in the blood of patients with cancer.”

2. Facet Wealth

Facet Wealth

Founded: 2016

Also honored in: 

“Facet Wealth is one of the fastest-growing financial services companies. By providing each client with their own CFP® professional to integrate unbiased financial advice into every facet of their life, at an affordable subscription price, we’re creating financial planning as it should be.”

3. b.well Connected Health

b.well Connected Health

Founded: 2015

Also honored in:

“b.well Connected Health enables the digital transformation in health care that consumers are demanding by providing an integrated platform. We have five core products that work together to deliver a configurable digital health experience for your populations. b.well provides health care stakeholders with the long-overdue technology for interoperability and aggregation that works horizontally across the system to consolidate consumer data and that works vertically to integrate point solutions. As a result, consumers have access to services and support that is timely and relevant to their needs.”

4. Protenus


Founded: 2014

Also honored in:

“Protenus helps hospitals protect patient privacy in electronic medical records by detecting privacy breaches in real-time. Our solution is a lightweight analytical tool focused on protecting against insider threats.

Built for overburdened hospital compliance & security officers, our analytics filter through the millions of activities that take place in a hospital every day in order to proactively identify HIPAA violations. Our solution deeply understands how patient data should be used and, as a result, can accurately determine when it is used improperly. We promise to help hospital compliance officers sleep soundly at night, knowing that all hospital employees are only using data within the bounds of their clinical or administrative responsibilities.”

5. Whitebox Technologies

Whitebox Technologies

Founded: 2013

Also honored in: 

“Brands and product manufacturers need a better way to get their products in the hands of consumers. The constant drumbeat of brick and mortar retail bankruptcies and store closings creates new pressure on brands and opportunity for those who can use tech smartly.

Today’s eCommerce marketplaces such as Amazon, Wal-Mart and eBay create hundreds of opportunities to drive growth and leverage technology.”

6. CraniUS


Founded: 2021

“CraniUS’ mission is to invent and engineer world-class technology to define the future of diagnostics and treatments for neurosurgical patients with brain disease.”

7. Insightin Health

Insightin Health

Founded: 2016

Also honored in: 2022 Best Tech Startups in Baltimore

“Insightin Health is the industry’s only single platform which provides a complete personalized member engagement for each steps of the health care journey. The core platform combines medical, clinical, cognitive, and social determinants of health to recommend the Next Best Action (NBA) for each person. Health plans can improve quality measurements, gain higher member satisfaction, and increase member retention. The simple integration and easy to use platform creates an effective shift towards healthier population for the health plans.”

8. Galen Robotics

Galen Robotics

Founded: 2016

“Galen Robotics is developing a single-platform solution to aid surgeons across several disciplines with minimal disturbance to existing workflows. Our cooperative control paradigm aims to eliminate hand tremor and enable surgeons to realize precise minimally invasive interventions in otolaryngology, head and neck surgery, and tissue reconstruction that were previously considered beyond human capacity.”

9. Cerebro Capital

Cerebro Capital

Founded: 2017

“The smarter way to get capital. Corporate lending marketplace. Cerebro Capital bridges the gap between mid-market business and top lenders with proven data-driven solutions.”

10. Americana Technologies

Americana Technologies

Founded: 2021

“Americana Technologies is the first marketplace to buy and sell physical things as NFTs.”