2022 Best Tech Startups in Cincinnati

Powered by CrunchbaseThe Tech Tribune staff has compiled the very best tech startups in Cincinnati, Ohio. In doing our research, we considered several factors including but not limited to:

  1. Revenue potential
  2. Leadership team
  3. Brand/product traction
  4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. Enable Injections

Enable Injections

Founded: 2011

Also honored in:

“Cincinnati-based Enable Injections is a healthcare technology innovator and startup developing and manufacturing large-volume wearable drug delivery systems – aiming to transform patient access to care by supporting flexible delivery, superior patient experience, and improved healthcare system value and economics.

Once approved by regulatory authorities, Enable’s wearable enFuse® drug delivery platform enables AnywhereCare TM – large-volume therapeutic delivery via subcutaneous administration in a healthcare clinic, with a healthcare professional at a patient’s home, or via self-administration at home.

Enable’s enFuse® utilizes standard container closure systems to deliver large volumes up to 50 mL of high-viscosity pharmaceutical and biopharmaceutical therapeutics. For more information, visit us at”

2. Physna


Founded: 2015

Also honored in: 

“Physna, short for “Physical DNA”, is a revolutionary technology that compares and analyzes 3D models through shape search, quality control and more in various industries. Physna is most commonly used in engineering and CAD design, manufacturing, aerospace, defense and diverse types of inspection automation. Physna is a fast-growing software company based in downtown Cincinnati, Ohio and is a Siemens partner as well as a technology provider to NASA Space Camp, Purdue University, etc.”

3. Astronomer


Founded: 2015

Also honored in:

“Astronomer helps organizations adopt Apache Airflow®, the leading open-source data workflow orchestration platform that helps organizations get their data in motion. Backed by Sierra Ventures, Bain Capital Ventures, AngelPad, CincyTech, Refinery Ventures, Wireframe Ventures, and Frontline Ventures, Astronomer is headquartered in Cincinnati, Ohio with offices in San Francisco, New York, and London.”

4. Coterie Insurance

Coterie Insurance

Founded: 2018

“What if small commercial insurance could be easy?

With Coterie Insurance, you can quote and issue policies in minutes! Whether directly through our site, through an independent agent, or with guidance from our support team, Coterie Insurance helps small businesses get the coverages they need when they need it so they can get back to what they do best.”

5. Losant


Founded: 2015

Also honored in:

“Losant is an easy-to-use and powerful enterprise IoT platform designed to help you quickly and securely build complex real-time connected solutions. Losant uses open communication standards to provide connectivity from one to millions of devices. Losant provides powerful data collection, aggregation, and visualization features to provide you with new data insights. Losant is trusted by your development team and capable of driving business results. Start independently or if you want help to define and build your unique product, Losant’s experienced solution engineers are ready to work with you.”

6. Relevate Health Group

Relevate Health Group

Founded: 2015

“To be relevant, your brand needs the right message. Delivered to the right audience. At the right time. In the right place. Consistently and continuously.

We are the only healthcare professional (HCP) engagement company to offer the flexibility of agency services and the power of proven products. Our results-driven approach improves brand performance at every stage, from pre-launch disease awareness through loss of exclusivity.

With Relevate Health as your partner, your brand benefits from local relevance on a national scale. Our proprietary, always-on delivery platform transcends typical campaigns to deliver continuous and scalable engagement that is right-on.”

7. enosiX


Founded: 2014

Also honored in:

“Delivering the perfect customer experience requires your SAP data to be accessible in real-time across your enterprise. Let our next generation of integration technology transform that experience into a competitive advantage by delivering on the promise of the intelligent enterprise.

enosix enables you to modernize your infrastructure by integrating SAP with any front-end system of engagement through an API-driven approach. Our integration solutions were created by former SAP executives with a vision for a smarter integration. The patent-pending enosix framework integrates and automates complex business processes across boundaries resulting in accelerated implementation and immediate ROI.”

8. Electrada


Founded: 2019

“Electrada is an emerging leader in transportation electrification, delivering performance-contracted, carbon-free electrification-as-a-service to corporate, government and institutional fleet customers across North America. Electrada’s unique, turnkey model integrates site energy engineering, supply optimization and fleet analytics into a fully-capitalized customer solution where the fleet owner eliminates the risks of electrification, while capturing predictable savings and sustainability outcomes for its stakeholders. Electrada’s solution ecosystem includes well-established fleet management, charging technology, microgrid and energy partners, dedicated to ROI-based decarbonization of transportation, across multiple vehicle classes and use cases.

Electrada, established in 2019, is headquartered in Cincinnati, and led by an executive team with proven expertise in tackling the complexity of the intersection of distributed energy and mobility.”

9. Cordata Healthcare Innovations

Cordata Healthcare Innovations

Founded: 2014

Also honored in: 2021 Best Tech Startups in Cincinnati

“Cordata Healthcare Innovations, previously Priority Consult, is a healthcare solutions company that develops highly specialized software applications for more effective patient management using patient-focused, nurse navigation models. Our solutions include Cordata Spine and Cordata Oncology.”

10. NaviStone


Founded: 2016

Also honored in: 2021 Best Tech Startups in Cincinnati

“NaviStone helps advertisers turn their website visitors into direct mail customers. We have invented technology that allows our clients to connect their browsers to postal name and addresses and enable retargeting via individualized direct mail, in a privacy compliant way. NaviStone features the industry’s only double blind system, ensuring these website visitors remain anonymous both to us and the website owner. We answer the Who/What/When to send direct mail more effectively than has ever been done.

NaviStone is located in historic Over-the-Rhine, the hub of Cincinnati’s vibrant innovation culture. We exist to create an environment where team members can reach their full potential. We are curious, relentless and fearless. We pride ourselves on hiring innovative professionals who are humble, respectful, caring and fun. NaviStone was honored to be named best in “Marketing Innovation” by the Cincinnati Business Courier in 2018.”