2025 Best Tech Startups in Mississippi
The Tech Tribune staff has compiled the very best tech startups in Mississippi. In doing our research, we considered several factors including but not limited to:
- Revenue potential
- Leadership team
- Brand/product traction
- Competitive landscape
Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.
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8. Citizen Health
Founded: 2017
Also honored in:
- 2024 Best Tech Startups in Mississippi
- 2021 Best Tech Startups in Mississippi
- 2020 Best Tech Startups in Mississippi
- 2020 Best Tech Startups in Hattiesburg
- 2019 Best Tech Startups in Hattiesburg
“At Citizen Health, we have a singular mission: to improve the lives of the 400+ million people navigating rare and complex conditions.
We empower patients with seamless access and control over their health data that they can share across our multi-sided platform with caregivers, providers and researchers to illuminate better treatment and support options, while bringing therapies to patients faster.
Led by a seasoned founding team with a history of success in healthcare and consumer startups, we are a mission driven startup team of builders, advocates, family caregivers, and researchers who have had first-hand experience across the spectrum of rare and complex diseases.”
7. HelloDank
Founded: 2024
“HelloDank is the industry’s wholesale platform built for users by users. Community-driven. Quality Focused.”
6. Tribly
Founded: 2020
Also honored in: 2024 Best Tech Startups in Mississippi
“Tribly is a direct-to-fan SaaS platform founded by artists, designed to help musicians grow their email and SMS lists. It offers a seamless way to convert followers into fans by providing early access to new music in exchange for vital contact information or lifetime pre-saves.”
5. Shovel
Founded: 2019
Also honored in: 2024 Best Tech Startups in Mississippi
“Shovel is a digital marketplace platform built for the pre-construction & mineral foundation industries. Shovel connects Builders, Material Pits, and Dump Trucks on 1 app, using 1 process, connected by 1 network.
Shovel standardizes project management, GPS tracks business activity, and automates payroll in the palm of your hand.”
4. HLX
Founded: 2020
Also honored in:
“Consider us your ultimate resource for connecting brands and communities on a deeper, more meaningful level. At HLX, we’re not just a platform; we’re your one-stop-shop for amplifying your presence and fostering genuine connections.”
3. Campusknot Inc.
Founded: 2015
“CampusKnot is an AI-powered teaching assistant that helps educators and their teams engage students, track participation, and identify learning gaps in real-time.
Our holistic approach to student engagement focuses on four key aspects: building a strong classroom community, gathering real-time feedback, ensuring academic integrity, and automating the upkeep of rewards. With AI-powered tools, you can supercharge🚀 your classroom, inspire collaboration, and save time—all while creating meaningful and impactful learning experiences for all students alike.”
2. WISPR Systems
Founded: 2017
Also honored in:
- 2024 Best Tech Startups in Mississippi
- 2022 Best Tech Startups in Mississippi
- 2021 Best Tech Startups in Mississippi
“Wispr Systems manufactures enterprise Unmanned Aircraft Systems (UAS) and turn-key payload solutions for commercial UAS applications.”
1. Lobaki
Founded: 2016
Also honored in:
- 2024 Best Tech Startups in Mississippi
- 2022 Best Tech Startups in Mississippi
- 2022 Best Tech Startups in Jackson
- 2021 Best Tech Startups in Jackson
- 2020 Best Tech Startups in Mississippi
- 2020 Best Tech Startups in Jackson
“Founded in 2017 in the heart of the Mississippi Delta, Lobaki is reinventing the way we educate and train the next generation of schools and companies with immersive simulations, virtual reality, and augmented reality experiences. With Mississippi roots and a desire to help push the state, students, and workers forward with emerging technology, Lobaki provides a competitive edge to helping educators and employers alike engage the next generation of students and workers.”