2025 Best Tech Startups in Oklahoma
The Tech Tribune staff has compiled the very best tech startups in Oklahoma. In doing our research, we considered several factors including but not limited to:
- Revenue potential
- Leadership team
- Brand/product traction
- Competitive landscape
Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.
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10. Boddle
Founded: 2018
Also honored in:
- 2024 Best Tech Startups in Oklahoma
- 2023 Best Tech Startups in Tulsa
- 2022 Best Tech Startups in Oklahoma
- 2022 Best Tech Startups in Tulsa
- 2021 Best Tech Startups in Tulsa
“Our mission is to engage grades K – 6 students in learning through our interactive game platform, and help equip teachers and parents to be better facilitators by identifying learning gaps early on and giving them effective tools to address these gaps.”
9. Progentec Diagnostics
Founded: 2015
Also honored in:
- 2024 Best Tech Startups in Oklahoma
- 2023 Best Tech Startups in Oklahoma City
- 2022 Best Tech Startups in Oklahoma
- 2022 Best Tech Startups in Oklahoma City
- 2021 Best Tech Startups in Oklahoma
- 2021 Best Tech Startups in Oklahoma City
“Progentec Diagnostics, Inc., was set up to explore and commercialize state of the art diagnostic interventions in therapeutic areas with a high level of unmet need. The company is collaborating with a number of research institutions and individuals around the world engaged in bringing the latest technological innovations to the field of diagnostics. The commitment to this cause is firmly rooted in our belief that better diagnostics would not only help in better and less costly management of diseases, but also help tremendously in reducing the incidence of diseases through early screening and detection.”
8. Volt
Founded: 2019
Also honored in:
“Volt is the leading Messaging Operations (Ops) infrastructure platform that enables software companies to integrate with multiple SMS providers and streamline number registration compliance and delivery reporting. Volt’s suite of solutions saves companies thousands of wasted engineering hours on building and maintaining their SMS compliance.”
7. The Zero Card
Founded: 2016
Also honored in:
- 2024 Best Tech Startups in Oklahoma
- 2023 Best Tech Startups in Tulsa
- 2022 Best Tech Startups in Oklahoma
- 2022 Best Tech Startups in Tulsa
- 2021 Best Tech Startups in Oklahoma
- 2021 Best Tech Startups in Tulsa
“At ZERO, we believe healthcare should be accessible, affordable, and free of financial barriers. Our mission is to simplify the healthcare experience by partnering with employers, providers, and members to remove cost as a barrier to care. Through innovative partnerships and bundled payment models, we ensure employees get the care they need at no out-of-pocket cost, while driving significant savings for employers.
With a focus on proactive member engagement and a commitment to delivering real, measurable results, ZERO is transforming how healthcare works for everyone.
Join us on the journey to make healthcare accessible, effective, and simplified to $0.”
6. RFX Solutions
Founded: 2021
Also honored in: 2024 Best Tech Startups in Oklahoma
“RFX Solutions offers an all-in-one regulatory compliance and credentialing solution designed to reinforce your healthcare facility’s culture of safety and optimize patient care. Featuring powerful, interactive modules, RFX helps you maintain a secure, compliant environment, ensuring your facility operates at its highest potential while benefiting from automated workflow processes. Visit us at www.rfxsolutions.com to learn more or schedule a demo.”
5. PatchRx
Founded: 2018
Also honored in:
“PatchRx is revolutionizing patient care through its clinically backed medication adherence technology. The company’s patented smart pill-bottle caps for generic prescription bottles, combined with its comprehensive software platform arms providers with the insight needed to assess a treatment’s effectiveness, and to intervene early to prevent adverse outcomes. PatchRx has improved care outcomes for thousands of patients across the U.S., closing the gap between a patient’s prescribed treatment and actual medication-taking behaviors.”
4. JackBe
Founded: 2020
Also honored in: 2024 Best Tech Startups in Oklahoma
“Striving to be your solution to online grocery through groundbreaking Tech Innovation!”
3. Medefy
Founded: 2018
Also honored in: 2024 Best Tech Startups in Oklahoma
“Medefy is a healthcare benefits navigation mobile platform that helps employers revolutionize their benefits offerings by empowering health plan members to find and use their health benefits — right when they need them. The platform provides a centralized tool that connects users with live benefits experts 24/7.”
2. Lumata Health
Founded: 2017
Also honored in: 2024 Best Tech Startups in Oklahoma
“At Lumata, we believe that proactive management of eye health is more important than ever. Our team transforms lives by preventing vision loss from chronic eye conditions like glaucoma, diabetic retinopathy, and macular degeneration. Our unique and innovative ophthalmology care management platform addresses complex barriers to treatment adherence, ensuring better clinical outcomes for thousands of patients—and we’re just getting started.
With a growing team of dedicated professionals across 40+ states, our employees make a difference every day. Our certified ophthalmic technicians and assistants work remotely as an extension of in-clinic staff, working closely with patients to provide personalized support. From managing treatment fatigue and navigating insurance issues to coordinating care and accessing social services, our team ensures patients have the tools, knowledge, and motivation needed to adhere to their care plans, improve their quality of life, and preserve their vision.”
1. Francis Energy
Founded: 2016
“Francis Energy’s mission is to create regional networks of public access electric vehicle charging equipment in order to encourage and support the widespread adoption of electric vehicles. Its business strategy is to develop, construct, and operate electric vehicle (“EV”) charging infrastructure projects in under-served rural and urban markets throughout the Midwest. Francis has a track record of success in developing and constructing EV charging infrastructure, including building and operating one of the largest EV charging networks in the USA.”