2022 Best Tech Startups in Brentwood

Powered by CrunchbaseThe Tech Tribune staff has compiled the very best tech startups in Brentwood, Tennessee. In doing our research, we considered several factors including but not limited to:

  1. Revenue potential
  2. Leadership team
  3. Brand/product traction
  4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. Groups360


Founded: 2014

Also honored in:

“Groups360 is on a mission to make group travel better for all. Our tech solution, GroupSync, brings innovation, transparency and simplicity to the decades-old industry problem of booking hotels for groups.

GroupSync is the first-ever distribution channel to offer online booking for both hotel rooms and meeting space. With over 200,000 properties already in its marketplace and nearly 7,000 ready for instant booking, GroupSync empowers travel planners and hoteliers to book groups while significantly reducing the effort and time it takes to do so.”

2. MDsave


Founded: 2012

Also honored in:

“MDsave is a healthcare technology company revolutionizing how hospitals and health systems increase access for the patient-consumer in an evolving market.

MDsave’s unique bundling technology makes medical procedures transparent, shoppable and instantly transactable. Through MDsave’s patented collection software, patients pay one upfront price for prospective or retrospective care, and payment is automatically distributed to all bundle participants within 4 days.

MDsave empowers patients to take control over their healthcare decisions and gives hospitals a seamless way to collect from patients. MDsave is co-located in Brentwood, Tenn., and San Francisco, Calif. For more information, visit”

3. MindCare Solutions

MindCare Solutions

Founded: 2013

Also honored in:

“MindCare is a leading provider of round-the-clock telepsychiatry and behavioral health services to hospitals, emergency departments, outpatient clinics, and correctional facilities. Our team of employed, board-certified psychiatrists, nurse practitioners, licensed clinical social workers and experienced healthcare administrators work collaboratively with your team to deliver the best quality care to your patients.

We partner with healthcare organizations to deliver best-in-class, end-to-end telebehavioral health services that combine evidence-based care pathways, advanced technology, and high-quality providers.”

4. Spiras Health

Spiras Health

Founded: 2015

“Spiras Health delivers comprehensive healthcare at home to patients at elevated risk of an emergency event or hospitalization. We improve quality of life, reduce hospital and ER visits and lower costs. Our services are provided in coordination with health plan provider networks, health plan care management departments and other programs. Spiras Health targets patients with one or more chronic diseases and those whose health status is complicated by co-morbidities, mental health issues, economic and social factors, access to services, and other social determinants. We deploy local Clinical Care Teams to provide home-based care that is tailored to the needs of each patient, while leveraging technology for cost-effective program delivery. Spiras Health is your health partner for life. Learn more at”

5. EvidenceCare


Founded: 2014

Also honored in: 2020 Best Tech Startups in Brentwood

“EvidenceCare is a unique clinical decision support system (CDSS) because of its EHR-integrated platform that optimizes clinician workflows to deliver better patient care, reduce hospital costs, and capture more revenue. Founded in response to the professional experience of emergency physician Dr. Brian Fengler, the platform provides clinicians with evidence-based care and measurable outcomes. To learn more, visit”

6. Valkyrie


Founded: 2020

“Valkyrie Investments is a specialized alternative asset management firm at the intersection of traditional finance and the emerging cryptocurrency sector. Headquartered in Nashville, Valkyrie aims to create and manage bespoke portfolios and products, including managing exposure to digital assets and other frontier investments. Valkyrie is led by seasoned asset managers who have previously launched multiple ETFs, publicly traded funds and ETPs, including bitcoin funds with backgrounds across Guggenheim Partners, UBS, Chicago Board of Trade, Chicago Mercantile Exchange, and The World Bank.”

7. Trilliant Health

Trilliant Health

Founded: 2017

Also honored in: 2020 Best Tech Startups in Brentwood

“Trilliant Health provides predictive analytics to the healthcare industry, creating unique evidence-based strategies for every customer. By synthesizing a variety of first-party and third-party data sets, Trilliant provides a comprehensive view into market dynamics, ensuring that healthcare decision makers find the most efficient and effective solutions to scale operations in current and future markets.”

8. Clarus Care

Clarus Care

Founded: 2013

“We ensure patient calls and messages always reach the right person and information is easily and accurately shared among healthcare teams – improving quality of care to patient and reducing risk to organization.

Utilize Clarus for daytime, after-hours, or 24/7 call management.”

9. Virsys12


Founded: 2011

Also honored in: 2020 Best Tech Startups in Brentwood

“We’re hiring and we need your help! If you or anyone you know is interested in joining our team, please let us know. See our job posting here

Virsys12 is a Salesforce Consulting Partner focused on healthcare innovation nationwide. With success providing transformative technology for payers, providers, healthcare services, and other industries, our team maintains top customer satisfaction and user adoption ratings. We solve your hardest problems by making the complex simple, guaranteeing our work for operational platform implementation, integrations, custom applications and technology strategy.

Passion is the key value that drives our “V12” culture. It’s been that way since we started. Virsys12’s values of integrity, collaboration, passion, and transformation guide how we work with each other and with our clients.”