2020 Best Tech Startups in Burlingame

Powered by CrunchbaseThe Tech Tribune staff has compiled the very best tech startups in Burlingame, California. In doing our research, we considered several factors including but not limited to:

  1. Revenue potential
  2. Leadership team
  3. Brand/product traction
  4. Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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1. Color


Founded: 2013

“Color’s mission is to help people lead the healthiest lives that science and medicine can offer. We launched in April 2015 with a simple, affordable genetic test to help people understand their risk for hereditary cancer. In 2017, we added coverage for hereditary heart conditions. Between them, cancer and heart disease constitute the two biggest causes of death worldwide. In September 2018, we introduced a new health area, medication response, to help people understand how their genes may influence response to certain medications.

By combining state-of-the-art software with clinical genomics, we’re building a personal health service that helps people benefit from the information in their own bodies. Early detection helps individuals create preventative plans with their doctors using appropriate screening guidelines relative to their personal and familial risk of certain diseases including cancer and heart disease.”

2. Lyra Health

Lyra Health

Founded: 2015

“Lyra Health’s mission is to transform mental health care through technology with a human touch — to get more patients the care they need when they need it. If you are an engineer or data scientist who would like to join in this effort, please reach out.”

3. Cala Health

Cala Health

Founded: 2014

“Cala Health is a bioelectronic medicine company transforming the standard of care for chronic disease. The company’s wearable neuromodulation therapies merge innovations in neuroscience and technology to deliver individualized peripheral nerve stimulation. The first indication for Cala Health’s wearable therapy is essential tremor, a disease experienced by more than seven million people and characterized by severe hand tremors. New therapies are under development in neurology, cardiology, and psychiatry. The company is headquartered in the San Francisco Bay Area and backed by leading investors in both healthcare and technology.”

4. Aperia Technologies

Aperia Technologies

Founded: 2010

“Aperia Technologies engineers innovation to make transportation more efficient, safer, and better for the environment. The company’s Halo® Tire Inflator and related products improve fuel economy and road safety while reducing tire expenditures and driver downtime for commercial fleets.”

5. Imply


Founded: 2015

“We are a technology company focused on real-time analytics with Apache Druid, and based out of Burlingame, CA. For more information, please email [email protected].”

6. The Yes

The Yes

Founded: 2018

“The Yes, a next generation AI-powered shopping platform poised to rewrite the architecture of e-commerce. Investors include NEA, Forerunner Ventures, True Ventures, Comcast Ventures and Bain Capital Ventures.”

7. Phantom AI

Phantom AI

Founded: 2016

“Phantom AI’s mission is to democratize the use of advanced driver-assistance systems (ADAS) to reduce accidents, save lives and make driving more enjoyable, while delivering tomorrow’s self-driving technology.

Founded by a team with deep automotive and AI expertise, Phantom AI provides a comprehensive autonomous driving platform featuring computer vision, sensor fusion and control capabilities. Phantom AI has created the most accurate and highest-performing AI solutions available today that meet car manufacturer requirements, at a much lower price than existing solutions.”

8. Trace Genomics

Trace Genomics

Founded: 2015

“Trace Genomics has developed the first analytics engine that learns as it maps the living soil. Founded in 2015 to serve the farming community, Trace Genomics helps agronomists and growers maximize the value of every acre. The company is building the largest, most actionable body of soil intelligence, making thousands of agronomists and growers experts on what’s underground. Working collaboratively across the agriculture ecosystem, Trace Genomics helps growers optimize costs, manage risk and protect their soil as a capital asset. Headquartered in Silicon Valley, Trace Genomics has raised $22.5 million in financing.”

9. Tesorio


Founded: 2013

“Our mission is to help companies grow faster by helping them understand and control their cash flow in real-time instead of just reporting on it. Strong cash flow generation is the single biggest determinant of a company’s ability to grow. It also affords management the freedom to optimize for long-term bets and truly innovate.

Jeff Bezos said it best in his letters to shareholders over a decade ago when he foreshadowed how he’d create a tech giant:

  • Measure Everything: “There is a right answer or a wrong answer, a better answer or a worse answer, and math tells us which is which” (2004)
  • Focus on Cash Flow: “Shares are worth only the present value of their future cash flows, not the present value of their future earnings” (2005)
  • Optimize for the Long-term: “Long-term thinking… supports the failure and iteration required for invention, and it frees us to pioneer in unexplored spaces” (2008)”

10. Focal Systems

Focal Systems

Founded: 2015

“Focal Systems was founded in 2015 with a very clear mission – automate and optimize brick and mortar retail.

With focalOS, we are providing the operating system of brick and mortar retail which enables retailers to operate truly data driven stores. focalOS leverages shelf-mounted cameras that constantly measure the state of customer facing shelves and use that data to optimize on-shelf availability, planograms, supply chain and in-store labor.”