2025 Best Tech Startups in Minnesota

April 2, 2025 thetechtribune

The Tech Tribune staff has compiled the very best tech startups in Minnesota. In doing our research, we considered several factors including but not limited to:

Revenue potential
Leadership team
Brand/product traction
Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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10. DUOS

Founded: 2020

“DUOS is reimagining the future of aging. As a technology-enabled service provider, DUOS connects people to the essential resources required to attain the highest level of health. Our advanced technology allows us to aggregate historically siloed data and resources from across the ecosystem, breaking down barriers to health literacy and access to care and enabling seamless and timely connections with complete visibility and feedback throughout the process.”

9. Fulcrum

Founded: 2020

Also honored in: 2023 Best Tech Startups in Minneapolis

“Fulcrum replaces ERP, MRP, and MES with a Manufacturing Software-as-a-Service (SaaS) platform, allowing small and mid-sized manufacturers to improve efficiency through workflow optimization and automated data collection. Fulcrum delivers value through a fully digital, paperless workflow leveraging machine learning, automation, predictive analytics, and advanced heuristics to drive throughput and profitability.

Software doesn’t have to be complicated. The software you use in your personal life (Facebook, Uber, Amazon, etc.) is intuitive, and you don’t need training to understand how it works. Why should your business software be any different? We’re helping manufacturers transition to cutting-edge, future-proof software that lowers the stress of everyday operations, gets more out of good employees who are difficult to hire, automates tedious tasks, and operates more efficiently than what exists in the manufacturing software space today.”

8. Nice Healthcare

Founded: 2017

Also honored in: 2023 Best Tech Startups in Minneapolis

“Nice Healthcare is redesigning comprehensive healthcare for small and medium-sized businesses by utilizing a mix of technology and in-home care. As an employee benefit, we offer employees and their families in-home and virtual primary care, virtual mental health therapy, and virtual physical therapy services. Our clinicians can also offer patients x-rays, 35 labs and blood draws and over 550 medications that can be prescribed with no out-of-pocket costs. Since launching in Minnesota in 2017, we’ve expanded our integrated care services to 12 states.”

7. Inbound Health

Founded: 2022

Also honored in: 2024 Best Tech Startups in Minnesota

“Inbound Health provides the full stack of capabilities that are required to scale at-home care models including home-based care pathways, virtual care teams, engagement and workflow technology, analytics, supply chain partnerships, operational oversight and payment models. The company’s flexible partnership structure enables customers to leverage their existing assets and capabilities while relying on Inbound Health to fill the gaps required to scale these programs across their service area.

To date, more than 8,000 patients across 350+ primary diagnoses have been cared for through the Inbound Health platform. The company combines biometric monitoring, digital surveillance, in-home nursing and therapy, virtual visits with hospitalists and geriatricians, and a comprehensive supply chain to deliver a safe and high-quality care program.”

6. Evolve Additive Solutions

Founded: 2017

Also honored in:

“For the first time in twenty years, a brand new and unique Additive Manufacturing technology emerges that represents the first industrial plug-and-play AM solution. A solution that can make the promise of Additive Manufacturing with real engineering plastics a reality. Our solution delivers the speed, quality, material selection and costs of injection molding, offering a truly viable alternative to traditional manufacturing.”

5. Inspectorio

Founded: 2015

Also honored in:

“Inspectorio is the leading AI-powered supply chain platform optimizing performance, building resilience, and providing intelligence across production chains for global brands, retailers, and their multi-tier suppliers.

Our innovative platform seamlessly connects and digitizes supply chain processes to optimize decision-making, while providing real-time visibility and control over production chain operations.

Today, Inspectorio is used by over 12,000 customers, including some of the largest brands and retailers in the world.”

4. CIBO Technologies

Founded: 2015

Also honored in:

“CIBO was founded by Flagship Pioneering in 2015 to apply advanced technologies to understand agricultural systems at any scale. We focus these capabilities on powering the transition to sustainable agriculture in order to mitigate climate change, secure the food system, and improve grower outcomes.

CIBO has developed a breakthrough approach to scaling and accelerating regenerative agriculture.

The CIBO Impact platform connects growers with enterprises ready to meet their sustainability, carbon, and Scope 3 commitments. Companies understand the emissions reduction potential of their agricultural supply chain, incentivize growers to make changes, verify practices, and quantify and report on results. Growers and their trusted advisors rapidly prequalify their land and understand the potential return of different incentive programs. The platform is built on advanced ecosystem simulation, AI, computer vision and software technologies, providing quantification, prediction, and insight capabilities at scale.”

3. Dispatch

Founded: 2016

Also honored in:

“Dispatch simplifies last-mile deliveries for businesses. Whether you’re looking for an established network of independent contractor drivers or to modernize your delivery experience with scalable scheduling software for your own vehicles, Dispatch is uniquely equipped to be your delivery partner so you can focus on what matters most to your business. Our delivery technology empowers you to Deliver More* for your customers.”

2. ShiraTronics

Founded: 2018

“ShiraTronics is a forward-thinking medtech startup committed to revolutionizing the field of migraine medicine with our minimally invasive neuromodulation system. Our mission? To transform the lives of those facing Chronic Migraine by reducing headache days and restoring quality of life.”

1. Branch

Founded: 2015

Also honored in:

“Branch is the leading workforce payments platform that delivers faster, more flexible options for people to get paid/”