2025 Best Tech Startups in Missouri

March 28, 2025 thetechtribune

The Tech Tribune staff has compiled the very best tech startups in Missouri. In doing our research, we considered several factors including but not limited to:

Revenue potential
Leadership team
Brand/product traction
Competitive landscape

Additionally, all companies must be independent (unacquired), privately owned, at most 10 years old, and have received at least one round of funding in order to qualify.

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10. Clever Real Estate

Founded: 2017

Also honored in: 2020 Best Tech Startups in St. Louis

“At Clever Real Estate, we envision a world where every person makes real estate moves that bring them closer to their life’s goals. To achieve that vision, we connect people with the most trustworthy advice and the best solutions for every step of their real estate journey.

We’ve built the leading online education platform in real estate: a portfolio of four digital content brands that reach over 10 million consumers per year with tools, advice and data to help them make better decisions.

And we’ve built a network of over 37,000 real estate professionals to help consumers take their journey with Clever offline, and reach better outcomes when they sell, buy, and move. Clever has a perfect 5.0 rating on TrustPilot — and our solutions have helped people save over $180 million on real estate fees.”

9. Invisibly

Founded: 2017

Also honored in: 2024 Best Tech Startups in Missouri

“Invisibly, founded by Jim McKelvey and backed by Peter Thiel’s Founders Fund, is the world’s first Gen-AI research panel that seamlessly merges AI-driven insights with consented human data to create Synthetic Audiences you can trust. Our innovative platform delivers instant, cost-effective insights with unmatched speed and accuracy, revolutionizing market research and empowering industries to leverage data for growth and innovation.”

8. Intramotev

Founded: 2020

Also honored in: 2023 Best Tech Startups in St. Louis

“Moving the world. One railcar at a time. https://www.youtube.com/watch?v=Hr2qCdcXD4I.”

7. Battle Financial

Founded: 2021

“The banking industry is long overdue for a revolution. No longer will clients have to settle for low-yield, high-fee banking partners or global products only available for the private banking clientele. Battle Bank will redefine digital banking — and do so with a focus on client experience, sophisticated solutions and better yields. Join the battle as we forge a radical new financial future.

Battle Bank is currently in its organizational phase and is not yet open for business, pending receipt of required regulatory approvals.”

6. Mylo

Founded: 2015

Also honored in:

“Mylo is an award-winning digital agency amplifying insurance solutions for companies who want to meet the coverage needs of small business owners and individuals.

Our embedded insurance platform combines data-driven technology, top-rated carrier partners, agents licensed in every state and deep insurance expertise.

The Mind of Mylo™ – our proprietary technology – makes precise coverage recommendations for every need, identifies the best carrier match and quotes the right policy at the best value. As our customers’ advocate, we specialize in safeguarding business assets and personal wealth.”

5. SimpleRose

Founded: 2018

Also honored in: 2024 Best Tech Startups in Missouri

“SimpleRose is a supercomputing company with a mission of enabling customers to optimize and accelerate decision-making. With the proliferation of data, growing business complexity, and importance of immediacy, data-to-insight is no longer sufficient. Our next-gen optimization platform and consulting services transform data-to-action, quickly and accurately, to maximize revenue / profit / productivity and minimize cost / time / wasted resources. Our proprietary technology solves some of the largest, most complex optimization problems in the world, thousands of times faster than alternative solutions. Our applications, including scheduling, production planning and portfolio optimization, can drive hundreds of millions of dollars in cost savings and/or revenue uplift.”

4. Balto

Founded: 2017

Also honored in:

“Uniting agents with AI for conversations that deliver results. Empower your team using real-time guidance with Balto.

Balto unites agents and supervisors with AI to power better agent performance. Agents and managers trust Balto’s real-time guidance to prevent missed sales opportunities, costly compliance mistakes, and negative customer experiences. Empowering agents results in happier customers, increased revenue, and better retention. Today, Balto has guided over 200 million calls, driven millions in increased revenue, and has a 4.8-star rating on G2.”

3. Paytient

Founded: 2018

Also honored in:

“Paytient helps people make better healthcare decisions by improving their ability to pay for care. We do this by bundling or embedding payment solutions like Paytient’s Health Payment Account (HPA) and the Medicare Prescription Payment Plan alongside commercial, individual ACA, and Medicare plans.

Armed with the power to decide how and when they pay for care, our users change their behavior in ways that improve their health and lower costs for everyone, which benefits plan sponsors.

By 2025, Paytient will serve 25M lives and 6,000 enterprise clients including leading employers and payers such as Anthem, Centene, Cigna, R.R. Donnelley, and Hyatt Hotels. The company has earned a 90 NPS and 4.9 stars on Trustpilot.”

2. Capacity

Founded: 2017

Also honored in:

“As support costs continue to rise, teams are often overburdened, struggling to maintain service levels while navigating increasing ticket volumes, and facing pressure to find cost-effective solutions to improve performance while managing growing demand.

Capacity is an omnichannel support automation platform that helps clients drive down support costs, improve knowledge access, and increase efficiency with practical and generative AI—so your team can do their best work. We offer solutions for intelligent virtual agents, employee enablement and agent assist, and process automation to nearly 20,000 companies worldwide.

Today, Capacity automates support over chat, SMS, voice, web, email, helpdesks, and more in one single platform, powered by technology and talent from Cereproc, Denim Social, Envision, Linc, Lucy, LumenVox, SmartAction, Textel, and YouCanBookMe.”

1. EquipmentShare

Founded: 2014

Also honored in:

“EquipmentShare is a nationwide equipment and digital solutions company serving the construction industry. We’re on a mission to give contractors and construction companies build with control thanks to our T3 technology platform and equipment rental, retail and service solutions.

We’re more than an equipment rental company. We share cloud-connected technology and equipment solutions that simplify construction work.

We’re always looking for curious, hardworking problem-solvers to add to our team! Check out our open positions and apply at equipmentshare.com/careers.”